Overview

DGL capsules helps to support digestion and peptic ulcers.  Gluten Free Dairy Free Vegetarian Vegan Non-GMO

Supports

• Digestion – peptic ulcers, H. pylori
• Intestinal & Urinary Inflammation
• Immunity: Dry Cough, Sore Throat, Laryngitis

Feature Ingredients

• DGL is the form associated with the greatest clinical efficacy, as it allows for licorice to be released in the stomach and dispersed/absorbed by the gastric mucosa. 
• Stimulates protective defenses, protects the GI lining & supports the health of the digestive system
• Deglycyrrhizination prevents adverse effects associated with licorice consumption

Details

Licorice root has been used for thousands of years in Eastern medicine for its soothing and decongestant properties.  Today, the benefits of licorice have been identified in its ability to soothe gastric ulcers, irritable bowel and acid reflux. It may also inhibit the growth of H. pylori, a bacterium often responsible for ulcers and heartburn symptoms. Unfortunately, licorice also contains compounds that can increase blood pressure, namely glycerrhizinic and glycerrhetinic acids. DGL-760 contains deglycyrrhizinated licorice,a licorice extract that does not contain these compounds and is safe for those who are concerned about its blood pressure raising effects.

AOR Advantage

AOR’s DGL-760 is ideal for anyone suffering from symptoms of bowel inflammation such as abdominal cramping, heartburn, bloating, gas, diarrhea and constipation.  DGL-760 reduces the risk of developing ulcers without the blood pressure raising effects of other licorice supplements.

•  Deglycyrrhizinated licorice, or DGL, has been used clinically for decades, primarily for the treatment of peptic ulcers.¹ 
• Licorice has been shown to inhibit several inflammatory enzymes, including both cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX), decreasing the production of several potent inflammatory compounds, including prostaglandin E2, thromboxane B2, and leukotriene B4.
• Importantly, this inhibition is not due to glycyrrhizic acid, the component of licorice which has been removed in DGL, and which is associated with mineralocorticoid excess and hypertension.² 
• Another component of licorice, glabridin, has been shown to prevent lipopolysaccharide (LPS) induced production of inflammatory compounds, including nitric oxide and interleukin-1 beta, whereas glycyrrhizic acid has no effect.
• Clinically, DGL has been shown to have comparable efficacy to cimetidine for both the healing and prevention of ulcer recurrences.³ 
• Additionally, extracts of licorice have been shown to inhibit the adhesion of H. pylori to gastric mucosa, as well as the growth of antibiotic resistant strains, suggesting multiple mechanisms of action for its anti-ulcer benefit.^4,5 The use of chewable tablets appears necessary for DGL’s efficacy, as it allows for distribution and absorption by the gastric mucosa.³

Ingredients

SKU: AOR04299: NPN: 80005124

Serving Size: 1 Vegetarian Capsule

Servings per Container: 60 Caps (20 Daily Servings of 3 Per Day)

Medicinal Ingredients

Allergens

Contains No: wheat, gluten, nuts, peanuts, sesame seeds, sulphites, mustard, soy, dairy, eggs, fish, shellfish or any animal byproduct. This product contains corn derived ingredients, do not use if you have an allergy.

Recommended Use

Adults 19+:  Take one capsule two times a day with/without food, or as directed by a qualified health care practitioner. Take a few hours before or after taking other medications. May be used up to four to six weeks.

AOR Advantage 

AOR puts pharmaceutical principles into practice to create the most effective products with the highest quality raw materials. Our processes allow us to ensure potency, purity and traceability from plant to product, giving our customers the certainty that they are always getting the same, effective formulation. We introduce and implement the latest testing strategies as part of our quality assurance process because we believe that it’s not about checking boxes, but how the boxes are checked that is important.

Contraindications

Do not use if you are hypersensitive or allergic to any of the ingredients. Do not use if you are pregnant or breastfeeding, have impaired kidney or liver functions, high blood pressure or heart disease or are a man with decreased libido.

Caution

Consult a health care practitioner prior to use if you are taking any medications or if you have any pre-existing condition. Discontinue 2 weeks prior to any scheduled surgery.

Consult a health care practitioner prior to use if you have diabetes or hypokalemia or are taking any kind of hormonal therapies, diuretics, potassium depleting agents, or MAO inhibitors.

No known drug interactions. Licorice influences the activity of several cytochrome enzymes, and reduces warfarin activity in animal models, likely due to glycyrrhizic acid activity. Thus DGL use should be carefully monitored in these patients.

Side Effect Risks

Discontinue use and consult a healthcare practitioner if symptoms persist, worsen or you develop any reactions which may include: allergy or intolerance.  Keep out of reach of children. Sealed for your protection. Do not use if seal is broken. For freshness, store in a cool, dry place.

Disclaimer

The information and product descriptions that appear on this website are for information and educational purposes only and are not intended to provide or replace medical advice to individuals from qualified health care professionals. Consult your physician if you have any health concerns, and before initiating any new dietary, exercise, supplements or other lifestyle changes.

References

1. Turpie AG, et al. Clinical trial of deglydyrrhizinized liquorice in gastric ulcer. Gut. 1969 Apr;10(4):299-302.
2. Chandrasekaran CV, et al. Dual inhibitory effect of Glycyrrhiza glabra (GutGard™) on COX and LOX products. Phytomedicine. 2011 Feb 15;18(4):278-84.
3. Morgan AG, et al. Comparison between cimetidine and Caved-S in the treatment of gastric ulceration, and subsequent maintenance therapy. Gut. 1982 Jun;23(6):545-51.
4. Wittschier N, et al. Aqueous extracts and polysaccharides from liquorice roots (Glycyrrhiza glabra L.) inhibit adhesion of Helicobacter pylori to human gastric mucosa. J Ethnopharmacol. 2009 Sep 7;125(2):218-23.
5. Fukai T, et al. Anti-Helicobacter pylori flavonoids from licorice extract. Life Sci. 2002 71:1449-63.