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A professional supplement that helps to support glucuronidation, a liver detoxification pathway.
Supports
- Nutrients: Calcium (9%)
- Detoxification
Feature Ingredients
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Calcium D-Glucurate 650 mg
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Calcium D-glucarate is made from calcium and glucaric acid which can be found in the human body as well as in fruits and vegetables such as oranges, apples, brussels sprouts, broccoli, and cabbage.
In a 2002 report published in Alternative Medicine Review investigators analyzed the available research on calcium-D-glucarate and found that it may lower estrogen and inhibit beta-glucuronidase, an enzyme associated with increased risk for various hormone-dependent cancers, such as breast, prostate, and colon when it occurs at elevated levels.1 It is believed to remove cancer-causing agents, toxins, and steroid hormones from the body.
A 2007 study published in Oncology Letters determined that calcium D-glucarate may help fight lung cancer.3 In tests on mice, researchers found that calcium D-glucarate helped inhibit the growth of cancerous tumors in the lungs by curbing inflammation and inducing apoptosis (a type of programmed cell death essential for stopping the proliferation of cancer cells).
There's also some evidence that calcium D-glucarate may protect against skin cancer. 4 For example, a 2007 study published in the Journal of Environmental Pathology, Toxicology, and Oncology found that treating mice with calcium D-glucarate helped suppress the development of skin cancer by inducing apoptosis.
Although calcium D-glucarate shows promise as an anti-cancer agent, more research including human trials is required.
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Serving Size: 2 Vegetarian Capsules (Twice Daily)
Servings per Container: 30 (15 Daily Doses)
Medicinal Ingredients
Each Capsule Contains:
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Calcium D-Glucurate |
650 mg |
Non- Medicinal Ingredients
Vegetable magnesium stearate and silicon dioxide in a non-GMO vegetable capsule composed of vegetable carbohydrate gum and purified water.
Allergens
Contains No Added: wheat, yeast, gluten, artificial colouring or flavouring, or dairy products.
Recommended Use
Adults 19+: Take 2 capsules twice daily or as directed by your health-care practitioner. Consult a health-care practitioner for use beyond 6 weeks.
Vitazan Advantage
Vitazan is a supplement company that is dedicated to research and high-quality products available through professionals only.
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Contraindications
Do not use if you are hypersensitive or allergic to any of the ingredients. Do not use if you are pregnant or breast-feeding.
Caution
Consult a health care practitioner prior to use if you are taking any *medications or if you have any pre-existing condition. Discontinue this product 2 weeks prior to surgery.
*Medication Interactions May Include: Lipitor (atorvastatin), Ativan (lorazepam), and Tylenol (acetaminophen). It may also temporarily reduce the levels of other steroid hormones in the body, such as testosterone.
Other drugs may interact with this product, including prescription and over-the-counter medicines, vitamins, and herbal products.
Side Effect Risks
Discontinue use and consult a healthcare practitioner if symptoms persist, worsen or you develop any reactions which may include: allergy or intolerance or digestive upset (constipation, nausea). Keep out of reach of children. Sealed for your protection. Do not use if seal is broken. For freshness, store in a cool, dry place.
Disclaimer
The information and product descriptions that appear on this website are for information and educational purposes only and are not intended to provide or replace medical advice to individuals from qualified health care professionals. Consult your physician if you have any health concerns, and before initiating any new dietary, exercise, supplements or other lifestyle changes.
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References
- Calcium-D-glucarate. Altern Med Rev. 2002;7(4):336-9.
- Hanausek M, Walaszek Z, Slaga TJ. Detoxifying cancer causing agents to prevent cancer. Integr Cancer Ther. 2003;2(2):139-44. doi:10.1177/1534735403002002005
- Zoltaszek R, Kowalczyk P, Kowalczyk MC, et al. Dietary D-glucarate effects on the biomarkers of inflammation during early post-initiation stages of benzo[a]pyrene-induced lung tumorigenesis in A/J mice. Oncol Lett. 2011;2(1):145-154. doi:10.3892/ol.2010.221
- Singh J, Gupta KP. Induction of apoptosis by calcium D-glucarate in 7,12-dimethyl benz [a] anthracene-exposed mouse skin. J Environ Pathol Toxicol Oncol. 2007;26(1):63-73. doi:10.1615/jenvironpatholtoxicoloncol.v26.i1.70
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Walaszek Z, Hanausek M, Narog M, Raich PC, Slaga TJ. Mechanisms of lung cancer chemoprevention by D-glucarate. Chest. 2004;125(5 Suppl):149S-50S.
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